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Supplementing TMLHE-knockdown cells or mildronate-treated cells with l-carnitine, but not KG, reversed sensitivity to DNA-damaging agents, confirming that KG was upstream of TMLHE-catalysed carnitine synthesis (Fig

Mhatre, M

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Activation of frataxin can enhance PINK1/Parkin-mediated mitophagy, which can significantly ameliorate lipid accumulation induced by a high-fat diet and free fatty acids [258, 259]

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doi:10.1111/jocd.14209