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conducted a CRISPR/Cas9 genetic screen with KEAP1 -mutant lung cancer cells and found that NRF2-addicted cancer cells are highly dependent on glutamine uptake, and that, consequently, inhibition of glutamine-derived glutamate by glutaminase inhibition effectively suppresses NRF2-addicted lung cancers (Romero et al

Population pharmacokinetic-pharmacodynamic (PKPD) modelling to describe the effects of paracetamol and N -acetylcysteine on the International Normalised Ratio (INR)

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Treatment within the same tattoo, or different tattoos on the same individual, may yield different results since the distribution of tattoo particles and how the body absorb them differ in the skin

& Schwabe, J