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Songorine promotes cardiac mitochondrial biogenesis via Nrf2 induction during sepsis

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Intraperitoneal injection of PMX500FI not only significantly reduced cell apoptosis in the photoreceptor layer of a mouse retinal detachment model and alleviated the inflammatory response accompanied by retinal detachment but also broadly protected the thickness of the outer nuclear layer, thereby maintaining the structural integrity and functional efficacy of the retina [322]