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Because oral dosing delivers the peptide directly to this tissue at high local concentration, it is the logical first choice for objectives like reflux-related irritation, inflammatory bowel-type inflammation, leaky-gut concerns, and general intestinal lining repair

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protection of the mitochondrial respiratory chain support for the efficiency of oxidative phosphorylation continuity of ATP production by supporting GSH Immunity and coordinated defensive response Immune cells make intensive use of glutathione

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A membrane-free gut-on-chip study revealed that candidalysin disrupts tight junction proteins (ZO-1, occludin) to induce leaky gut, and further induces intestinal epithelial cells (IECs) apoptosis and necroptosis, thereby exacerbating barrier breakdown 111