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GLP-1 has a very short half-life of 12 minutes due to rapid degradation by the enzyme dipeptidyl peptidase-4 (DPP-4)

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Significant alterations at 12 h with an APAP lethal dose were observed for ALT levels and 12 miRNAs: 574-5p, 135a*, 466 g, 1196, 466f-3p, 877, 342-3p, 195, 375, 29c, 148a and 652