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Confirmatory secondary endpoints included exercise function assessed by change in 6MWD, overall clinical benefit assessed using a hierarchical composite endpoint (all-cause death, HF events, several thresholds of change in KCCQ-CSS from baseline to 52 weeks and change in 6MWD 30 m) and change in CRP from baseline to 52 weeks

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Inject consistently on the same day each week The 168-hour half-life means weekly injections maintain stable plasma levels

Comparison of hepatic oxidative DNA damage in patients with chronic hepatitis B and C

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