Nearly 40% of adults age 60 and older qualified as obese in 2023, according to the Centers for Disease Control and Prevention
Zmora, N., Suez, J., & Elinav, E
Strategic dose titration The clinical trial protocol starts at 1mg weekly and escalates every 4 weeks through 2mg, 4mg, 8mg, and potentially 12mg
Adding cagrilintide at a moderate dose (1.0-2.4 mg) provides amylin-mediated appetite suppression through a completely different neuronal circuit, which may allow you to use a lower retatrutide dose (8 mg instead of 12 mg) while achieving comparable or superior total metabolic effect
Injectable GLP-1s may be more suitable for: Patients aiming for the maximum possible reduction in body weight, those with co-existing conditions like heart disease or chronic kidney disease (due to specific FDA approvals for Ozempic), or those who prefer a simple weekly medication schedule
Together, they mimic GLP-1s metabolic benefits, helping you maintain weight loss after GLP-1 without feeling overwhelmed