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These can affect how side effects manifest and how strong they are

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If diarrhea persists beyond six weeks or worsens, consulting your healthcare provider is important to rule out other causes or discuss dose adjustment strategies

Still, side effects are possible for about 40% of people, including nausea, diarrhea, stomach pain, vomiting, constipation, heartburn, loss of appetite and cravings and an aversion to foods

Retatrutide is a novel investigational medicine currently in clinical development