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This can cause lightheadedness, fainting, and an incredibly rapid heartbeat (an increase in over 30 beats per minute or over 120 beats per minute total within 10 minutes of getting up)

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Diabetologia (1996) 39:154653

The combination does not necessarily preclude either intervention, but thyroid function should be tested before starting, at six weeks, and at three months to ensure levels remain within range

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The mechanisms by which these supplements claim to work lack the robust scientific validation required for therapeutic claims