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Elevated circulating IGF-1 led to an activation of the IGF-1PI3KAkt signalling pathway, causing augmented mTOR phosphorylation and higher phospho-FoxO/total FoxO ratio in skeletal muscle of LC supplemented rats [33]

The most common places where individuals taking Ozempic may develop blood clots are in the deep veins in the legs, leading to deep vein thrombosis (DVT) and the lungs, resulting in pulmonary embolism (PE)

*Correspondence: Yi Wang, [email protected]

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doi: 10.1016/j.enceco.2025.05.001 9 LiuYKangWLiuSLiJLiuJChenXet al