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10.1136/bmj.287.6396.876 Br Med J

Studies have also reported stimulation of proteoglycan and collagen synthesis in chondrocyte preparations, pointing to a meaningful role in joint research independent of its metabolic activity

The most important results of previous evolution from the eight children are shown in black and the follow up is present in blue ( Table 1 )

Injection Schedules: Weekly injections remain on usual schedule

These shortages have had a significant impact on patient care

Notwithstanding the impressive results that have been published to date, there is still a requirement for successful human trials to be completed prior to clinical translation