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Each SNP represents one difference in a building block of DNA

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Semaglutide 2.4 mg (Wegovy): ~15% body weight loss at 68 weeks in clinical trials Tirzepatide 15 mg (Zepbound): ~21% body weight loss at 72 weeks in clinical trials Real-world data shows lower results: Cleveland Clinic research from 2025 found average weight loss of 7.7% with semaglutide and 12.4% with tirzepatide at one year in routine clinical practice

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Mistake 4: The Math Meltdown

Discontinuation of GLP1RAs and tirzepatide typically results in weight regain, deterioration of glycaemic control and the loss of previous improvements in cardiometabolic markers