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Senescent-like microglia, in contrast, limit remyelination through SASP that involves the release of multiple inflammatory mediators, including CCL11, CXCL9, and CCL5, and increased expression of IL-2, leading to impaired remyelination in mouse models (Gross et al., 2025)

[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Uzel B.P.C., Takano G.H.S., Chartuni J.C.N., et al

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