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European data show prevalence rates of approximately 300 cases per 100,000 individuals in Finland, 206 per 100,000 in Austria and 147 per 100,000 in Boston

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The VPA-induced ASD model group showed significantly higher dissimilarity from the control group, indicating profound dysbiosis

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The controlled nature of clinical trials may not fully capture the diverse and dynamic conditions encountered in real-world settings

However, neuronal differentiation was decreased by 60%, as measured by the number of cells double stained with BrdU and DCX (Figure 5a, c)