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Free radicals are a natural byproduct of metabolism, but are unstable and highly reactive molecules that, in excess, can damage other cells
yet, both in vitro and in vivo studies demonstrate that enteric commensals can rapidly stimulate the generation of free radicals upon contacting epithelial cells 90
Both the brand-name product and its generic version contain the same active ingredient and offer the same therapeutic benefits
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However, results vary from person to person, and they are not guaranteed
Notably, genes involved in the TSS pathway, cystine uptake and glutathione recycling (such as CBS, CSE, SLC7A11 and GSR) were DNA hypomethylated after DMF treatment 30 , supporting a regulatory effect of DMF on these pathways
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