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doi:10.1016/j.biopha.2023.114936 Tucker M, Keely A, Park JY, et al

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N-number: RNA sequencing utilized N=12 for the IP group and N=24 for the IN group

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Clinical trials are ongoing with small-molecule TNF--converting enzyme, p38 mitogen-activated protein kinase and phosphodiesterase inhibitors that specifically interrupt the synthesis and signalling pathways for TNF- and downstream pro-inflammatory molecules such as IL-1, IL-6, nitric oxide synthase and cyclooxygenase-2

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M.MartineauA.HaahtelaT.et al

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Over time, that stress can affect nerve tissue and blood vessels

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Cell culture The murine KK-1 granulosa cell line (a gift from Ilpo Huhtaniemi, Imperial College, UK) was cultured as reported [110], maintained at 37 C with 5% CO 2 at 3080% confluency, passaging 23 times a week

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