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Obviously, there is not a definite translation between mice and humans but the results are certainly worth keeping in mind

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Accordingly, substituting the acidic and polar residues surrounding the degraders sulfinic group with nonpolar amino acids, as well as substituting adjacent T63 with a negatively charged aspartic acid, attenuated this activity (Fig

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Consequently, for proximity labeling applications with LaccID, BMP is recommended to maximize sensitivity and BP is recommended to maximize spatial specificity