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Many people find that injecting in the evening reduces the impact of any nausea, since they sleep through the peak absorption window

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The Antidiabetogenic Effect of GLP-1 Is Maintained During a 7-Day Treatment Period and Improves Diabetic Dyslipoproteinemia in NIDDM Patients

Severe constipation requiring medical treatment or medication discontinuation remains rare, occurring in less than 2% of trial participants

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As well, excessive dietary protein that is above the needs for repair or growth can be converted to fat by the liver and increase visceral adiposity (Mozafariun et al 2025)