Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein
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If the amount of fat exceeds what the body needs, abnormal fat accumulations may develop in the liver, causing an increase in liver enzymes and inflammation
In contrast, the buildup of lipid ROS and the consequent onset of ferroptosis can be hindered through intervention with iron-chelating agents (e.g., deferoxamine) and lipophilic antioxidants (e.g., ferrostatin-1 and liproxstatin-1) [77]
It is still challenging to estimate the scale to which host genetics shape the configuration of the gut microbiota [128,129]
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