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Begin with a 7-day core detox or reset that eliminates processed foods, cuts back on alcohol, and resets your sleep and hydration habits

The fundamental mechanism is the activation of phase II detoxification enzymes or antioxidase controlled by Nrf2/ARE, including the expression of NAD(P)H quinone dehydrogenase 1 (NQO1), GPX, and superoxide dismutase (SOD) (Truong et al., 2014)

found increased cellobiose excretion and decreased mannitol excretion in a 5 h urine collection in patients with active celiac disease (77)

Oxidative stress plays a significant role in the pathogenesis of GO and GD (the balance between oxidants and antioxidants is disturbed in favor of ROS), and an antioxidant approach is proposed for treatment (85, 86)

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Rutschmann, O., Toniolo, C