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AOD 9604 does not affect appetite, blood sugar, or hormone levels in any meaningful way

Primary human hepatocytes (PHH) were obtained from BioIVT (donors IAN, IPH, GID) and from Lonza (donors HUM4108, HUM4055B, HUM4229, HUM181501B)

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Xie X, Wang X, Shi X, Zhang Y, Laster KV, Liu K, et al

The tirzepatide injection is subcutaneous, not oral, so gastric emptying has no effect on tirzepatide absorption

Here, they undergo incomplete, alternative oxidation pathways that generate massive amounts of free radicals and reactive oxygen species (ROS), further damaging the delicate mitochondrial membranes and the very enzymes required for energy production