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Grocott methenamine silver staining of brain sections from the infected mice showed that PEG-ITP-Lip/AmB significantly reduced the amount of C
However, this same mechanism is responsible for many of the gastrointestinal side effects commonly reported by patients
However, this effect can diminish over time (tachyphylaxis) and varies in intensity throughout the treatment course
It remains in late-stage clinical trials as of 2026
Researchers will be observing various outcome measures throughout the process, including percent change from baseline in BMI, body weight, waist circumference, blood pressure, cholesterol, and fasting blood glucose, among other measurements