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41 Despite the different hypotheses behind the etiology of headaches in COVID-19, authors such as Bobker & Robbins et al propose that headaches in the early stages of COVID-19 are most likely due to systemic infection while headaches in later stages can be explained by neuroinvasion and cytokine release storm

Table 5: * Nasal or inhaled corticosteroids have less effect

Gamma-glutamyl transferases has been considered an early marker of neoplastic transformation

Serine proteases have also been identified in pyrethroid-resistant maize weevil ( Sitophilus zeamais ), suggesting this resistance mechanism is broad-spectrum across many insect species 33,39

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