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Historically, milk kefir was discovered in the Caucasian region while water kefirs history remained unclear (Rosa et al., 2017)

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Exendin-4, a GLP-1RA, upregulated hepatic ABCA1 via the CaMKK/CaMKIV/PREB pathway and alleviated fatty liver in HFD-fed mice [39]

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Acknowledgements This work was supported by a project (HI21C0694, Development of treatment for intractable skin diseases using low-molecular compounds with enhanced Wnt/beta-catenin) funded by the Ministry of Health and Welfare, Republic of Korea and by the National Research Foundation of Korea(KRF) grant funded by the Korea government(MSIT) (RS-2025-16072747)