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The mRNA and protein expression of the GSH biosynthesis pathway (GCLC, GCLM, GSS, and GSR) were downregulated in GCLC knockdown cells (Fig

Each component has been independently studied in preclinical research for its proposed role in cellular repair, tissue responses, and molecular signaling

eLife 7 , e37503 (2018)

To further validate lineage-specific differentiation at the molecular level, parallel samples were collected after 14 days of induction for RT-qPCR analysis

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Pharmaceutical companies could collaborate to conduct clinical validation regarding its efficacy in treating specific health conditions