Such structural modification has been applied to exenatide, lixisenatide, semaglutide, dulaglutide, and albiglutide
Tirzepatide (Mounjaro, Zepbound) is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, not a pure GLP-1 agent
Roche with its 2024 acquisition of Carmot, and Pfizer, following its 2025 acquisition of Metsera, enter obesity and broaden their presence in cardiovascular/metabolic, while other large pharmaceutical companies prepare to follow later in the decade
Tirzepatide is a newer medication that targets two specific hormones, which enhances the medications effects even further
This was driven especially by the reduced major adverse cardiovascular events found to result from the addition of these drugs to antidiabetic regimens
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