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The BOLS model and the coreshell structure have been applied to other size dependencies of nanostructures such as the mechanical strength, chemical and thermal stability, lattice dynamics (optical and acoustic phonons), Photon emission and absorption, electronic colevel shift and work function modulation, magnetism at various temperatures, and dielectrics due to electron polarization etc

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It is studied for its involvement in cellular signaling pathways, structural protein support, regenerative processes, and oxidative stress models