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It is better described as more active at MC1R, rather than fully selective, since most melanocortin peptides can act on multiple receptors

2008;31(6):E31927

95,96 Both electroencephalography and resting-state fMRI data support the presence of increased functional coupling between the auditory cortex and the anterior frontal attention network, 9799 consistent with the necessity of long-range connectivity for conscious sound perception