The impact of BMI on treatment response is well illustrated by the AQUILA study, which examined real-world outcomes in PsA patients treated with (65).In this cohort, obese individuals exhibited higher circulating levels of IL-17, supporting the concept that IL-17driven inflammation may be particularly prominent in this subgroup and may contribute to increased disease activity and reduced therapeutic responsiveness (66)
Story Source: Materials provided by American Heart Association
These findings suggest that the gut microbiota may promote the onset and progression of EDC through the propagation of inflammatory signals that activate both peripheral and central immune responses
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Association of cumulative loneliness with all-cause mortality among middle-aged and older adults in the United States, 1996 to 2019
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