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Dysregulated inflammatory mediators and microbial products, such as cytokines (e.g., TNF, IFN, IL-1, IL-22) and endotoxins, are closely linked to barrier dysfunction and impaired intestinal homeostasis [10]

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Furthermore, glutathionylated residue C151 of roGFP2 reacted three to four times faster than glutathionylated residue C208, which is again the opposed reactivity as observed for the oxidation kinetics of both monothiol roGFP2 variants (Table 1)

Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) affects up to 10 million people in the U.S., mostly women, causing chronic pain, frequent or urgent urination, and discomfort

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