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Curr Opin Pharmacol (2013) 13(6):9649

Ipamorelin: H-Aib-His-D-2Nal-D-Phe-Lys-NH2 Dual-Receptor Class Pharmacology of GHRH-R Agonism and GHS-R1a Agonism This preparation contains two peptides that engage two chemically distinct G-protein-coupled receptors expressed on the same target cell population (the anterior pituitary somatotroph) through different second-messenger pathways

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FDA-approved GLP-1 medications for weight loss are typically indicated for adults with obesity (BMI of 30 or higher) or adults with overweight (BMI of 27 or higher) who also have at least one weight-related medical condition

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