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The inflammatory cytokines, particularly tumour necrosis factor alpha (TNF), interleukin-1 (IL-1) beta and interleukin-6 (IL-6), appear to be the primary mediators of cachexia

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doi: 10.1016/S2468-2667(20)30062-1 [DOI] [PubMed] [Google Scholar] 8.Julien J, Ayer T, Tapper EB, Barbosa C, Dowd WN, Chhatwal J