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A double-blind, randomized, placebo-controlled study

(Wang et al., 2022)

It may reflect low copper, malnutrition, malabsorption, excessive zinc, liver or kidney disease, or an inherited copper disorder

Elevated Hcy levels result in heightened excitatory glutamatergic neurotransmission in various brain regions, contributing to neuronal damage

Generation of GFP-tagged cell lines HepG2-GFP reporter cell lines expressing tagged Nrf2, HMOX1, or SRXN1 were constructed with bacterial artificial chromosomes that encode C-terminal GFP-tagged fusion proteins as described previously (Wink et al