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numerous fish and rodent models have shown that long-term MPs exposure disrupts gut microbiota structure and amplifies local inflammation [73]

Understanding these multifaceted benefits helps explain why this peptide has generated significant interest in both research and clinical settings

Beyotime, Shanghai, China) was used to detect ROS generation in pancreatic tissue sections

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10.1016/s0140-6736(16)32410-2 51 HawrylukG

In contrast to the aforementioned RCD types, ferroptosis exhibits higher dependence on transition metals, particularly iron, and it does not require caspase action but relies on the oxidative activity of Fe 2+ , which is its main distinguishing feature