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Additionally, to close the gap between genetic discoveries and clinical practice-particularly in the case of sickle cell anaemia-efforts are being made to establish bioinformatics infrastructure in areas with high occurrences (89)

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Similar to PilQ, we interpret these observations to indicate that at high concentrations and/or high temperatures, these secretins irreversibly aggregate and fail to enter the gel (ref

Cardiovascular applications and other metabolic uses contribute a combined share of around 10%, reflecting emerging therapeutic potential