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Kazunori Nakashima (Organization of Advanced Science and Technology, Kobe University) for their helpful discussion

This can be important given GABAARs, as members of the Cys-loop family of pentameric transmembrane ligand-gated ion channels, expressed in parts of the nervous system that process higher-order brain functions and have influences on regulating synaptic transmission and integration of synaptic signals central to memory, awareness, and consciousness [226]

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J Virol

Neither compound is metabolized through shared enzymatic routes