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Subcutaneous is the most common route for general systemic delivery

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Serotonin receptors are present on peripheral nerve fibers and play roles in pain modulation and nerve fiber maintenance

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Clinical Studies on B12 & Neuropathy Methylcobalamin: A Potential Vitamin of Pain Killer PMC article: This review covers methylcobalamins analgesic and nerve-repair effects in diabetic neuropathy and other neuropathic pain states