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Metabolic dysfunction is at the root of many chronic diseasesincluding type 2 diabetes, fatty liver disease (NAFLD), cardiovascular disease, and even certain cancers

Procyanidins: a promising antidiabetic agent with potential benefits on glucose metabolism and diabetes complications

Glucagon-like peptide-1 relaxes rat conduit arteries via an endothelium-independent mechanism

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They have different dosages and recommendations tailored to their respective uses

Figure 1 summarizes a conceptual overview rather than a single experimental model, developed on the basis of published evidence, with the aim of facilitating the understanding of central and peripheral pathways involved in the GI effects associated with GLP-1 receptor agonists