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The STEP 1 extension trial showed that participants regained approximately two-thirds of lost weight within one year of stopping semaglutide [18]

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For patients with severe B12 deficiency, we may recommend an initial loading phase of daily or weekly injections to quickly restore B12 levels

In patients with high-risk or very-high-risk chronic kidney disease, the mean decline in estimated glomerular filtration rate was smaller in the tirzepatide group than in the dulaglutide group

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