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I remember both of us looking at the data, and we looked at each other and said, Well, this is going to be a drug. From Bench to Bedside By the 1990s, scientists found that injecting GLP-1 into rats reduced their appetites

Safety and side effects were similar to those of previously approved GLP-1 receptor agonists

Recent reviews (March 2026) consistently praise the welcome calls from team members

This led to further double-blinded, randomized, placebo-controlled trials examining the effects of semaglutide and tirzepatide in patients with obesity, but who did not have type 2 diabetes

People with type 2 diabetes have an 84% higher baseline risk of developing pancreatitis compared to the general population

Individual results vary based on health history, adherence, and other factors