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Conclusion The absence of weight loss with GLP-1 therapy is not a contradiction but a reflection of its broader metabolic effects

How many calories should I eat while on semaglutide

The findings in our study reinforce that exercise cannot be optional for people taking these medications

Stacks are discussed for experimental design only

For mild to moderate joint discomfort without red flag features, management should be guided by NICE NG226 (Osteoarthritis in over 16s: diagnosis and management) and may include: Exercise and physiotherapy , which are central to NICE-recommended management