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Any one of those events with a sub-spec solvent can degrade the remaining doses in the vial

10.1124/jpet.103.052225 262 ZhangS.LiR.DongW.YangH.ZhangL.ChenY.et al (2019b)

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Introduction Evidence from trials and real-world studies in patients with type 2 diabetes (T2D) indicates that the risk of complications may be reduced by providing sustained glycemic control and that near-normal glycated hemoglobin (HbA 1c ) levels should be achieved as early as possible in the T2D trajectory (1, 2)

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