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By integrating signalling markers with perfusion-based measurements, researchers can characterize circulation-related adaptations with greater analytical depth and experimental precision

Nasal bioavailability for systemic effects is low, but the nose-to-brain pathway delivers oxytocin directly to central receptors with good efficiency

altering its production may affect downstream pathways in ways not yet studied long-term

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A recent study showed that TET activity, controlled by the -KG competitor itaconate (ITA), critically regulates human macrophage functions 44