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Superoxide dismutase in gastric and esophageal, cancer and the prognostic impact in gastric cancer

J Neurol 2022 Correll CU et al

Here we show, by directing the biosynthesis of -glutamylcysteinethe immediate glutathione precursorto mitochondria, that it efficiently detoxifies hydrogen peroxide and superoxide anion, regardless of cellular glutathione concentrations

While the peptide has been studied for decades and has shown promising results in animal research, there is currently insufficient clinical evidence to establish the peptide therapys safety and effectiveness in humans

Targeting Galectin As A Strategy To Improve BH3 Mimetic Efficacy For The Therapy Of Acute Myeloid Leukemia

Ferroptosis, a regulated cell death pathway, is closely linked to oxidative stress and lipid peroxidation, triggered by an accumulation of lipid hydroperoxides derived from polyunsaturated fatty acids [10]