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Jeong et al, Adv

"Effect of Methylsulfonylmethane Pretreatment on Aceta-minophen Induced Hepatotoxicity in Rats"

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Positivity for islet cell autoantibodies in patients with monogenic diabetes is associated with later diabetes onset and higher HbA1c level

Animal models of colitis have demonstrated that GLP-1 receptor activation may reduce intestinal inflammation through multiple mechanisms, including modulation of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-) and interleukin-6 (IL-6), enhancement of intestinal barrier function, and reduction of oxidative stress

Functional in vitro characterization demonstrated that BiSpekDAb bound IL-23 and TNF- with EC50 values of 11.39 2.7 nM and 12.72 8.25 nM, respectively