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In short, while its true that some people taking GLP-1s have had changes to their bone health, these changes seem to be driven primarily by magnitude of weight loss rather than a direct, negative consequence of the medications themselves, Dr

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A Cox proportional hazards model was used to test for non-inferiority against the pre-specified risk margin of 1.3 for the hazard ratio (HR) of the composite of CV death, myocardial infarction (MI), or ischemic stroke (MACE) and if non-inferiority was demonstrated, to test for superiority on the two primary endpoints: 1) the composite of hospitalization for heart failure or CV death, and 2) MACE

Van Long et al., 2014

Al-Kuraishy HM, Al-Gareeb AI, Eldahshan OA et al (2024) The possible role of nuclear factor erythroid-2-related factor 2 activators in the management of COVID-19