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Stopping treatment prematurely can lead to serious neurological complications

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[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Birben E., Sahiner U.M., Sackesen C., Erzurum S., Kalayci O

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However, one factor responsible for the limited effectiveness of B cell depletors in progressive MS may be resistance of leptomeningeal inflammation to even intrathecally administered agents for reasons that are not understood (Bhargava et al., 2019)

Similar data were found for the detergent, deoxycholic acid (180), but anecdotally care should be taken not to inject too much detergent that can remain in the tissue requiring excision to remove