semaglutide glycine methylcobalamin with glycine: what it is, how it works, and why compounding pharmacies add it Compounded Semaglutide with B12: Everything

Your provider will review your health history and goals before recommending any protocol

Biochem J 431(2):169178

It isnt specifically approved for MC4R deficiency specifically, only for weight management and appetite control in adults and children with POMC- , PCSK1- , or LEPR- deficient obesity or those with genetically confirmed pathogenic variants, likely pathogenic variants, or variants of uncertain significance in POMC , PCSK1 , or LEPR (FDA: 2 years of age and older

The lowest dose of the GLP-1 pill, 1.5 mg, can cost $149 per month

People seem to love carnitine supplements

Or they may require you to try multiple cheaper drugs first to make sure something more affordable doesn't do the trick (this is called step therapy)