Sleep-related impairment (SRI) refers to cognitive, emotional, and functional disturbances caused by insufficient or low-quality sleep, including daytime fatigue, decreased concentration, and diminished work performance [143]
The TRIUMPH program includes seven other Phase 3 trials (TRIUMPH-1 general obesity 80 weeks, TRIUMPH-2 obesity+T2D, TRIUMPH-3 obesity+CV disease, plus T2D, OSA, and CVOT) with readouts expected during 2026
Archives of Biochemistry and Biophysics , 387 (2), 273-280
Finucane OM, Sugrue J, Rubio-Araiz A, Guillot-Sestier MV, Lynch MA
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In addition, the GLP-1 agonists may make some drugs more aversive or unpleasant, says Luba Yammine, an associate professor of psychiatry at UTHealth Houston who is currently the principal investigator of a clinical trial evaluating a GLP-1 agonist as a potential treatment for smoking cessation and post-cessation weight management