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14 Discussion While the herbal formulations and their active compounds, standalone or in combination, have demonstrated robust in vitro efficacy, translation to in vivo and clinical settings remains variable, and oftentimes a large therapeutic barrier

(1976) 90-day dermal toxicity of DDVP in male rats

(PubMed) Ghadirian P, Jain M, Ducic S, Shatenstein B, Morisset R

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J Genet Genomics Yi Chuan Xue Bao

7-HMR also lowered the levels of proinflammatory mediators: brain tissue analyses revealed decreases in TNF- and iNOS (inducible nitric oxide synthase) with 7-HMR therapy (62)